Genetics, ecology, and evolution of adaptive traits
-An R35-MIRA award from the National Institute of General Medical Sciences will fund the lab from 2021-25. The $1.25million grant is titled: "Mining natural infection variation to find the genetic basis of coevolution between vertebrate hosts and helminth parasites"
-Check out our newest preprint on the evolution of immunity to tapeworms: Evolution of a costly immunity to cestode parasites is a pyrrhic victory
We use an integrative approach, drawing from practically every biological discipline, to describe the process of adaptation via natural selection. We not only love the organisms and traits that we study, but also believe that broadly focused research is critically important during this period of increasing specialization in science. In addition to adding to the foundation of basic evolutionary science, by studying adaptations that have survived the gauntlet of natural selection, we are poised to mine a largely untapped reservoir of solutions to pressing medical and conservation challenges.
What genetic changes drive variation in ecologically relevant
(i.e. adaptive or functional) traits?
How are host-parasite interactions influenced by coevolution
within and among populations?
How do variable selection and developmental plasticity
influence the molecular architecture of adaptive traits?
Can we predict and follow natural selection in action?
How to learn more?
Please visit the research and publication pages for info on previous and ongoing work,
and don't hesitate to contact Jesse with any questions.
Scientific American: The Evolution of Architecture, by Robb Dunn.
New York Times: Study Discovers DNA That Tells Mice How to Construct Their Homes, by James Gorman.
NationalGeographic.com: Phenomena Blog. The Genes That Built a Home, by Ed Yong.
BBC News: Mouse burrowing "in their genes."
Science Magazine: ScienceNow News. Building a Better Mouse Burrow Requires Few Genes, by Elizabeth Pennisi.
Nature: News and Comment. Behaviour Genes Unearthed, by Patrick Goymer.
ScienceMag: News Focus. How Beach Life Favors Blond Mice, by Elizabeth Pennisi.
A great animation by Harvard University undergraduate student Arian Kam. Inspired by my PhD dissertation on the genetics of burrwing behavior in deer mice. Weber et al 2013
A beautiful video, produced by the Howard Hughes Medical Institute, that describes the Bolnick Lab's field
research on Vancouver Island. I collaborate with Dan Bolnick on numerous threespine stickleback projects, and also use Vancouver Island lakes, streams and estuaries as field sites.